Nalbuphine and slow release morphine
نویسندگان
چکیده
منابع مشابه
Respiratory function following nalbuphine and morphine in anaesthetized man.
In 40 patients anaesthetized with thiopentone, 66% nitrous oxide and 1% halothane, the effects of a single i.v. dose of nalbuphine 4.5, 8, 15, 25 or 50 mg/70 kg or morphine 3, 5, 10 or 17.5 mg/70 kg on total ventilation and end-tidal carbon dioxide concentration have been measured. Depression of respiration occurred with both drugs and with all doses. The lower doses of nalbuphine produced more...
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Two groups of 40 patients undergoing hip replacement received either nalbuphine 0.3 mg kg-1 or morphine 0.15 mg kg-1 i.m. on up to three occasions: 1 h before operation, as soon as requested after operation, and 3 h subsequently if required. Pain intensity was assessed by the patient as severe, moderate or none, and pain relief by a "blind" nurse observer as slight, moderate or complete. Assess...
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OBJECTIVE The aim of the present study was to test the efficacy of epidural nalbuphine 5 mg for prevention of morphine-induced pruritus. MATERIAL AND METHOD Parturients, ASA I-II scheduled for elective cesarean section under epidural anesthesia were randomized into 3 groups: the placebo group, N-5 group, and N-10 group received 4 ml epidural solution containing morphine 4 mg plus either salin...
متن کاملEffect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets
BACKGROUND Injections of mixtures prepared from crushed tablets contain insoluble particles which can cause embolisms and other complications. Although many particles can be removed by filtration, many injecting drug users do not filter due to availability, cost or performance of filters, and also due to concerns that some of the dose will be lost. METHODS Injection solutions were prepared fr...
متن کاملPharmacokinetics and analgesic effect of slow-release oral morphine sulphate in volunteers.
Sustained-release oral morphine sulphate (MST) 20 mg was administered to 11 healthy volunteers. Mean peak plasma morphine concentration was 14.8 ng ml-1, and occurred at a mean time of 142.5 min after ingestion. Analgesia assessed by an ischaemic forearm pain test increased to a maximum approximately 40 min after the calculated peak plasma concentration of morphine had been achieved, and remain...
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ژورنال
عنوان ژورنال: BMJ
سال: 2004
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.328.7453.1426